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Human Chromosomes (4th Edition)

Author(s):
Publisher:

Springer

Pages: 501
Further Actions:

Recommend to library

AVAILABLE FORMATS

Paperback - 9780387950464

06 October 2000

€94.94

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Hardcover - 9780387950310

06 October 2000

€126.59

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Ebook - 9781461301394

28 June 2011

€74.96

In stock

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This is the fourth edition of an acclaimed introductory textbook on the structure and function of human chromosomes. The explosion of information on human genetic diseases has meant that there is a greater need than ever for...

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This is the fourth edition of an acclaimed introductory textbook on the structure and function of human chromosomes. The explosion of information on human genetic diseases has meant that there is a greater need than ever for students, practising physicians, laboratory technicians, and researchers to have a concise, up-to-date summary of the normal and abnormal behavior of chromosomes. This book continues to fulfill that need, and is strengthened by the complete revision of material on the molecular genetics of chromosomes and chromosomal defects.

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1 Origins and Directions of Human Cytogenetics
2 The Mitotic Cell Cycle
3 DNA Replication and Chromosome Reproduction
4 General Features of Mitotic Chromosomes
5 The Chemistry and Packaging of Chromosomes
6 Chromosome Bands
7 Molecular Correlates of Chromosome Bands
8 In Situ Hybridization
9 Main Features of Meiosis
10 Details of Meiosis
11 Meiotic Abnormalities: Abnormal Numbers of Chromosomes
12 Abnormal Phenotypes Due to Autosomal Aneuploidy or Polyploidy
13 Chromosome Structural Aberrations
14 The Causes of Structural Aberrations
15 Syndromes Due to Autosomal Deletions and Duplications
16 Clinical Importance of Translocations, Inversions, and Insertions
17 Sex Determination and the Y Chromosome
18 The X Chromosome, Dosage Compensation, and X Inactivation
19 Phenotypic Effects of Sex Chromosome Imbalance
20 Fragile Sites, Trinucleotide Repeat Expansion, and the Fragile X Syndrome
21 Euploid Chromosome Aberrations, Uniparental Disomy, and Genomic Imprinting
22 Chromosome Changes in Cell Differentiation
23 Somatic Cell Hybridization in Cytogenetic Analysis
24 Chromosome Instability Syndromes
25 DNA and Gene Amplification
26 Genome Destabilization and Multistep Progression to Cancer
27 Chromosomes and Cancer: Activation of Oncogenes
28 Chromosomes and Cancer: Inactivation of Tumor Suppressor Genes
29 Mapping Human Chromosomes
30 Genome Plasticity and Chromosome Evolution
31 The Future of Human Cytogenetics.
From the reviews of the third edition                                   "Each word "tells" in this concise gem of a human cytogenetics text...Superb organization makes this an excellent text...for any cytogenetics course."- American Journal of Human Genetics"
...the leading textbook in English on human cytogenetics."- Cell
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